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Nanotechnology Insititute


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Robin Liu

Dr. Robin Liu is currently a Manager of Microfluidics Technology at Combimatrix Corp. His responsibilities involve development of integrated DNA microarray biochips, microfluidic system for sample preparation and DNA analysis, and integrated immuno- sensors. Prior to joining Combimatrix, he was a Manager and Co-founder at Applied NanoBioscience Center, Arizona State University (ASU) in 2003. He worked on microfluidics, fuel cells, nano-biotechnology, etc. Prior to joining ASU, he was a Principal Scientist and Group Leader at Motorola Inc (2000~2003). He worked on integrated microfluidic labchips and DNA microarray biochips. Dr. Liu was a summer intern at Aclara Biosciences, Inc. (1999), working on plastic chip microfabrication and integrated sample prep on a chip.

Dr. Liu received his Ph.D. degree in mechanical engineering from University of Illinois at Urbana-Champaign in 2000. Dr. Liu is an inventor of 6 US patents (issued and pending), and the author of 47 scientific publications and 4 book chapters. He served on the International Steering Committee of several international conferences, including the 26th Annual International Conference of IEEE Engineering in Medicine and Biology Society (Track Chair), 2001 International MEMS Workshop in Singapore, the 2nd Annual International IEEE Conference on Microtechnology, Medicine, and the 2003 International Conference on Materials for Advanced Technologies in Singapore. He received 2 BRAVO awards and 22 Silver Quill Awards from Motorola. He is currently an Associate Editor for the SPIE Journal of Microlithography, Microfabrication, and Microsystems.


Integrated Microfluidic Biochips for Immunoassay and DNA Bioassays

Bioassays involve multi-stage sample processing and fluidic handling, which are generally labor-intensive and time-consuming. Using microfluidic technology to integrate and automate all these steps in a single chip device is highly desirable in many practical applications such as clinical diagnostic and in-field environmental testing. We have recently developed self-contained and fully integrated microfluidic biochips for immunoassay and DNA analysis. These microfluidic biochip devices can perform detection of multiple bioagents (including antigens and DNA) using fluorescent or electrochemical detection methods. The devices with capabilities of on-chip sample processing and detection provide a cost-effective solution to direct sample-to-answer biological analysis.


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