Description
Bioreactors and fermenters lie at the heart of processes used to produce both large and small-molecule therapeutics. These reactors must produce an axenic environment that is conducive to and optimizes the growth and productivity of microorganisms ranging from fragile cells to robust bacteria.

This seminar provides a detailed review of the factors that contribute to successful design and operation of cGMP bioreactors, featuring in-depth lecture and discussion on bioreactor mixing and mass transfer principals, as well as practical applications for process development and scale-up. Bioreactor cleaning, sterilization and equipment design fundamentals will be presented individually and then brought together in case study and workshop format, illustrating key concepts. New trends and developments in the application of single-use technology and disposable bioreactors to upstream bioprocessing will also be discussed.

What You Will Learn

• How to define bioprocess requirements for bioreactors and fermenters
• Inter-relationships between vessel geometry and agitator mass transfer, heat transfer and blending capability
• Vessel and hardware design features and their impact on aseptic performance
• Application of single-use technology to upstream bioprocessing
• Integration of CIP/SIP into the reactor process

Who Should Attend
Engineers, scientists and production personnel involved in the design of bioreactors and fermenters, as well as component and system suppliers, end-users and engineering design firms. Operations personnel can gain an improved understanding of bioreactor and ancillary equipment capability and operating strategies.

Instructor/Speaker Panel

• Seminar Director: David Marks, PE, President, DME Alliance Inc.
• Paul Chen, Associate Director of Cell Culture Development, Biogen Idec
• Wei Huang, Director of Process Engineering, Fluor Corp
• Paul Kubera, Vice President, Engineering, ABEC, Inc.
• Alvin W Nienow, PhD, DSc (Eng), Emeritus Professor of Biochemical Engineering, University of Birmingham
• Tom Warf, Consultant

SCHEDULE

REGISTER NOW! Visit www.asmeconferences.org/BioprocessEurope08

ASME Travel Policy : ASME is not responsible for the purchase of non-refundable airline tickets or the cancellation/change fees associated with canceling a flight. Please call to confirm that the course is running before purchasing airline tickets. ASME retains the right to cancel a course up until 3 weeks of the scheduled presentation date.